The HIV/AIDS Clinical Trials Networks have mobilized in response to the global pandemic and provided key support for COVID-19 vaccine and therapeutic research efforts. Studies and COVID-19 research collaborations in which the HIV/AIDS Clinical Trials Networks are involved are listed below.
Leveraging the infectious disease expertise, research infrastructure, and community partnerships of the existing HIV/AIDS research networks, the networks have responded to the need for vaccines, monoclonal antibodies, and therapeutics against SARS-CoV-2 infection. Announcements and public communications from the networks are found below:
Find resources on how to become a participant in clinical research, community engagement materials, important social media accounts to follow, webinars on COVID-19 and other useful information.
Behavioral insights for people with COVID-19 as well as those living with HIV.
Since the COVID-19 pandemic began, researchers with existing longitudinal cohorts and survey samples have been developing and fielding new survey items assessing various COVID-19 specific domains such as symptoms, knowledge and attitudes, adherence to various mitigation behaviors, social impacts, and economic impacts. Efforts to standardize or harmonize COVID-19 survey items, however, did not appear feasible given the urgency to field items as early as possible during the pandemic.
To minimize the proliferation of one-off survey items, encourage comparisons across samples, and facilitate data integration and collaboration, a trans-NIH working group co-led by the National Institute on Aging (NIA) and the Office of Behavioral and Social Sciences Research (OBSSR) worked to make existing COVID-19 survey items and investigator contact information available in a survey item repository. Two NIH-supported survey item platforms have made this expanding list of survey items available as a resource for researchers interested in assessing COVID-19 specific domains.
Researchers addressing COVID-19 questions, whether population-based or for clinical research, are encouraged to consider these COVID-19 specific survey item repositories and select existing survey items or protocol modules currently being fielded. Researchers with additional survey items about to be fielded are encouraged to make them public for other researchers to consider by submitting the survey to NIHCOVID19Measures@nih.gov.
Provided by the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). Revised April 8, 2020.
What is the goal of these questions?
A group of researchers from Nemours, CHOP and Cincinnati have developed a questionnaire designed for insertion into ongoing and new child health studies where aspects of the COVID-19 pandemic may impact study findings. The COVID-19 Exposure and Family Impact Survey (CEFIS-19) is in English and Spanish. There are also have REDCap versions. While designed for research, there may also be clinical applications. There is no charge for use, but it is requested that you register your work as the survey is covered by the SAMHSA-funded Center for Pediatric Traumatic Stress in the National Child Traumatic Stress Network. The Healthcare Toolbox has related COVID-19 materials that are updated and, in some cases, newly developed.
Shared by Anne E. Kazak, Ph.D., ABPP, Director, Center for Healthcare Delivery Science, Nemours Children’s Health System, Co-Director, Center for Pediatric Traumatic Stress (www.healthcaretoolbox.org), Professor, Department of Pediatrics, Thomas Jefferson University, Editor-in-Chief, American Psychologist.
Compiled by the Center for Drug Use and HIV | HCV Research (April 11, 2020). This site includes the following items:
This COVID-19 Quantitative Questionnaire was developed for MTN042/MTN-043, two trials in sub-Saharan Africa with pregnant (MTN-042/Deliver) and breastfeeding (MTN-043/B-protected) women.
The Pandemic Stress Index Survey
The Pandemic Stress Index is a measure of behavior changes and stress related to the COVID-19 pandemic developed at the University of Miami. The survey is available in Spanish, Turkish, Italian, Mandarin, Creole, Arabic, Portuguese, Lithuanian, and Greek.
This document provides guidance to Member States in the WHO European Region that wish to conduct behavioural insights studies related to COVID-19. The COVID-19 pandemic outbreak is placing an overwhelming burden on health systems and authorities to respond with effective and appropriate interventions, policies and messages. A poorly timed and managed pandemic response or transition phase can threaten the gains collectively achieved. The pandemic and its restrictions may have affected mental and physical well-being, social cohesion, economic stability as well as individual and community resilience and trust. In this complex context, understanding how, why and the context in which humans and communities respond allows to:
Population surveys can explore perceptions, acceptance of restrictions, mental and physical health, behaviours, information needs, misperceptions and more.
The COVID-19 pandemic has impacted the operations, capacity, and processes among laboratories affiliated with the HIV/AIDS Clinical Trials Networks. Announcements and guidance specific to labs are found below.