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Title

An Evaluation of Methods to Improve the Reporting of Adherence in a Placebo Gel Trial in Andhra Pradesh, India.

Authors

Abbott SA, Friedland BA, Sarna A, Katzen LL, Rawiel U, Srikrishnan AK, Shalini CS, Tun W, Kelly CA, Solomon S, Mensch BS.

Network Affiliation

Other

Organization

 

Journal Name

AIDS Behav.

Publication Date

1/1/2013

PubMed Search

http://www.ncbi.nlm.nih.gov/pubmed/23299877

Link to full-text

 

PMID

 

Abstract

Female sex workers (FSWs) were recruited for a 4-month placebo vaginal gel trial in Nellore, India. Two experiments explored if prior knowledge of biomarkers for unprotected sex and insertion of gel applicators would yield more accurate self-reports. A third experiment compared self-reports of gel use and adherence levels between FSWs randomly assigned to interactive voice response survey (IVRS) and those assigned to paper diaries. Prior knowledge of biomarkers did not improve accuracy of self-reported condom or gel use, nor did it affect actual adherence. Of those who tested positive for the presence of semenogelin in the vagina, 76 % reported no unprotected sex in the previous 48 h. Overall, women reported using gel on 90 % of days whereas the biomarker indicated gel use on fewer than 50 % of days. Compliance to IVRS was low, despite familiarity with mobile phone technology. Additional explorations with other populations are needed.

Keywords

 

Topic

Adherence; Behavior; Novel Technologies; Women

Attachments

Created at 1/24/2013 1:56 PM by Davis, Gregory P
Last modified at 1/24/2013 1:56 PM by Davis, Gregory P