Objective: We investigated the awareness and acceptability of pre-exposure prophylaxis (PrEP) among men who have sex
with men (MSM) and potential predicting factors.
Methods: This study was conducted among MSM in Beijing, China. Study participants, randomly selected from an MSM
cohort, completed a structured questionnaire, and provided their blood samples to test for HIV infection and syphilis.
Univariate logistic regression analyses were performed to evaluate the factors associated with willingness to accept (WTA)
PrEP. Factors independently associated with willingness to accept were identified by entering variables into stepwise
logistic regression analysis.
Results: A total of 152 MSM completed the survey; 11.2% had ever heard of PrEP and 67.8% were willing to accept it.
Univariate analysis showed that age, years of education, consistent condom use in the past 6 months, heterosexual behavior
in the past 6 months, having ever heard of PrEP and the side effects of antiretroviral drugs, and worry about antiretroviral
drugs cost were significantly associated with willingness to accept PrEP. In the multivariate logistic regression model, only
consistent condom use in the past 6 months (odds ratio [OR]: 0.31; 95% confidence interval [CI]: 0.13–0.70) and having ever
heard of the side effects of antiretroviral drugs (OR: 0.30; 95% CI: 0.14–0.67) were independently associated with willingness
to accept PrEP.
Conclusions: The awareness of PrEP in the MSM population was low. Sexual behavioral characteristics and knowledge
about ART drugs may have effects on willingness to