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Title

The Spread of HIV in Pakistan: Bridging of the Epidemic between Populations

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Network Affiliation

Other

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Journal Name

PLoS One

Publication Date

7/25/2011

PubMed Search

 

Link to full-text

 

PMID

21799857

Abstract

In the last two decades, 'concentrated epidemics' of human immunodeficiency virus (HIV) have established in several high risk groups in Pakistan, including Injecting Drug Users (IDUs) and among men who have sex with men (MSM). To explore the transmission patterns of HIV infection in these major high-risk groups of Pakistan, 76 HIV samples were analyzed from MSM, their female spouses and children, along with 26 samples from a previously studied cohort of IDUs. Phylogenetic analysis of HIV gag gene sequences obtained from these samples indicated a substantial degree of intermixing between the IDU and MSM populations, suggesting a bridging of HIV infection from IDUs, via MSM, to the MSM spouses and children. HIV epidemic in Pakistan is now spreading to the female spouses and offspring of bisexual MSM. HIV control and awareness programs must be refocused to include IDUs, MSM, as well as bisexual MSM, and their spouses and children.

Keywords

 

Topic

Adolescents/Youth; Behavior; MSM; Substance Abuse; Women

Attachments

Created at 9/23/2011 9:18 AM by Davis, Gregory P
Last modified at 9/23/2011 9:18 AM by Davis, Gregory P