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Title

Transmission Clustering Drives the Onward Spread of the HIV Epidemic Among Men Who Have Sex With Men in Quebec

Authors

Bluma G. Brenner, Michel Roger, David Stephens, et al.

Network Affiliation

Other

Organization

 

Journal Name

Journal of Infectious Diseases

Publication Date

9/1/2011

PubMed Search

 

Link to full-text

 

PMID

 

Abstract

Phylodynamic analysis and epidemiologic data identified 3 patterns of spread of primary human immunodeficiency virus type 1 infection (PHI) among men who have sex with men (2001-2009): 420 unique PHIs, 102 small clusters (2-4 PHIs per cluster, n = 280), and 46 large clusters (5-31 PHIs per cluster, n = 450). Large clusters disproportionately increased from 25.2% of PHIs in 2005 to 39.1% in 2009 (χ(2) = 33.9, P < .001). Scalar expansion of large clusters over 11 months (interquartile range, 3.5-25.5 months) correlated with cluster membership size (r(2) = 0.174, F = 4.424, P = .047). PHI cohort data revealed variations in social networks and risk behaviors among the 3 groups, suggesting the need for tailored prevention measures.

Keywords

 

Topic

Behavior; MSM; Network theory/studies

Attachments

Created at 9/2/2011 1:31 PM by Davis, Gregory P
Last modified at 9/2/2011 1:31 PM by Davis, Gregory P