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Title

Expanding the Menu of HIV Prevention Options: A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States.

Authors

 

Network Affiliation

 

Organization

 

Journal Name

AIDS and Behavior

Publication Date

12/30/2017

PubMed Search

https://www.ncbi.nlm.nih.gov/pubmed/29290075

Link to full-text

 

PMID

29290075

Abstract

Adherence challenges with oral pre-exposure prophylaxis have stimulated interest in alternate modes of administration including long-acting injections. We conducted 30 in-depth interviews with 26 male trial participants and 4 clinical providers in a Phase IIa study (ÉCLAIR) evaluating the use of long-acting cabotegravir (CAB-LA) injections in New York and San Francisco. Interviews exploring attitudes and experiences with CAB-LA were audiotaped, transcribed, and analyzed using thematic content analysis. Despite a high frequency of some level of side effects, almost all participants reported being interested in continuing with CAB-LA, versus a daily oral, due to its convenience and the perceived advantage of not worrying about adhering to pills. Providers reinforced the importance of CAB-LA as a prevention option and the need for guidelines to assist patient decision-making. Further research is needed on the acceptability of CAB-LA among men and women at higher risk for HIV in different settings.

Keywords

 

Topic

Adherence; Behavior; Women; qualitative research

Attachments

Created at 1/25/2018 10:33 AM by Davis, Gregory P
Last modified at 1/25/2018 10:33 AM by Davis, Gregory P