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Title

Perceptions and experiences with VOICE adherence strengthening program (VASP) in the MTN-003 trial

Authors

A. van der Straten, A. Mayo, ER Brown, et al.,

Network Affiliation

Other

Organization

 

Journal Name

AIDS and Behavior

Publication Date

11/1/2014

PubMed Search

http://www.ncbi.nlm.nih.gov/pubmed/?term=25384907

Link to full-text

 

PMID

25384907

Abstract

​The VOICE Adherence Strengthening Program (VASP) was implemented in May 2011 to improve adherence counseling in VOICE (MTN-003), a multisite placebo-controlled trial of daily oral or vaginal tenofovir-based Pre-Exposure Prophylaxis (PrEP). Anonymous baseline (N = 82) and final follow-up (N = 75) surveys were administered to counselors and pharmacists at 15 VOICE sites, and baseline (N = 18) and final (N = 26) qualitative in-depth interviews were conducted with purposively selected counseling staff at 13 VOICE sites. Qualitative interviews with VOICE participants (N = 38) were also analyzed for segments related to counseling. Behavioral and biological measures of product use collected in the 6 months prior to VASP implementation were compared to those collected during the 6 months following implementation. Results show that the majority of staff preferred VASP and thought that participants preferred VASP over the previous education and counseling strategy, although there was no evidence to suggest that participants noticed modifications in the counseling approach. No meaningful changes were observed in pre/post levels of reported use or drug detection. Interpretation of results is complicated by mid-trial implementation of VASP and its proximity to early closure of oral and vaginal tenofovir study arms because of futility.

Keywords

 

Topic

Adherence; Behavior; Black; Women

Attachments

Created at 2/17/2015 9:55 AM by Davis, Gregory P
Last modified at 2/17/2015 9:55 AM by Davis, Gregory P