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Title

Condom effectiveness for HIV prevention by consistency of use among MSM in the US

Authors

DK Smith, JH Herbst, X. Zhang, CE Rose

Network Affiliation

Other

Organization

 

Journal Name

JAIDS

Publication Date

12/1/2014

PubMed Search

http://www.ncbi.nlm.nih.gov/pubmed/25469526

Link to full-text

 

PMID

25469526

Abstract

OBJECTIVE::

We derived an estimate of male condom effectiveness during anal sex among men who have sex with men (MSM) because the most widely used estimate of condom effectiveness (80%) was based on studies of persons during heterosexual sex with an HIV-positive partner.

DESIGN::

Assessed male condom effectiveness during anal sex between MSM in two prospective cohort studies of HIV incidence by self-reported consistency of use.

METHODS::

Analyzed data combined from US participants in the EXPLORE trial (1999-2001) public use dataset and in the VAX 004 trial (1998-1999) dataset. Initially HIV-uninfected MSM enrolled in these trials completed baseline and semiannual interviews about their sexual behaviors with male partners and underwent HIV testing. Using a time-to-event model, effectiveness of consistent condom use in preventing HIV infection was estimated among men reporting receptive and/or insertive anal sex with an HIV-positive partner, and consistency of condom use.

RESULTS::

Among MSM reporting any anal sex with an HIV-positive male partner, we found 70% effectiveness with reported consistent condom use (compared to never use) and no significant protection when comparing sometimes use to never use. This point estimate for MSM was less than the 80% effectiveness estimate reported for heterosexuals in HIV discordant couples reporting consistent condom use. However, the point estimates in the two populations are not statistically different. Only 16% of MSM reported consistent condom use during anal sex with male partners of any HIV status over the entire observation period.

CONCLUSIONS::

These estimates are useful for counseling efforts, and for modeling the impact and comparative effectiveness of condoms and other prevention methods used by MSM.

Keywords

 

Topic

Behavior; MSM

Attachments

Created at 12/12/2014 12:00 PM by Davis, Gregory P
Last modified at 12/12/2014 12:00 PM by Davis, Gregory P